Behcet's Disease ResearchConcomitant colitis in a patient with Behcet's disease.Primary Author: Yusuf YilmazPrimary Author: Department of Internal Medicine, Uludag University School of Medicine, Uludag University Hospital, Bursa, Turkey.Date Published: 2008 12 23Abstract: Abstract not available
Successful treatment for sympathetic storms in a patient with neuro-Behçet's disease.Primary Author: Takahisa GonoPrimary Author: Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-Ku, Tokyo, 162-0054, Japan.Date Published: 2008 12 22Abstract: Sympathetic storms (SyS) are characterized by hyperactivity of autonomic functions, resulting in episodes of hyperthermia, hypertension, tachycardia, and hyperhidrosis. We show here a patient with neuro-Behçet's disease (NBD) complicated by SyS. Although SyS is well known to occur with brain tumors, trauma, and hydrocephalus, this is the first report to show that SyS is a manifestation of central nervous system involvement in a patient with NBD. High concentrations of norepinephrine (NE) and IL-8 in cerebrospinal fluid reflected the activity of SyS. The patient's symptoms showed almost complete improvement after treatment with corticosteroids and intravenous cyclophosphamide. Also, the concentrations of NE and IL-8 were decreased to normal levels. An awareness of the potential for SyS and adequate immunosuppressant therapy are of importance when dealing with patients with NBD.
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